Gene Detail

Gene Symbol CREBBP
Synonyms CBP | KAT3A | RSTS | RSTS1
Gene Description CREBBP, CREB-binding protein, plays a key role in transcription regulation for a number of different genes involved in a variety of cellular processes including proliferation, differentiation, apoptosis, and DNA repair (PMID: 27380996, PMID: 20435671). Expression, mutations and chromosomal translocations of CREBBP have been associated with various human cancers (PMID: 23839013; PMID: 21390130; PMID: 23022987; PMID: 9290955), including glioblastoma and leukemia (PMID: 21390130, PMID: 21390126, PMID: 25423036).
Entrez Id 1387
Chromosome 16
Map Location 16p13.3
Canonical Transcript NM_004380


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