Gene Detail


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Gene Symbol CRKL
Gene Description CRKL, CRK like proto-oncogene, adaptor protein, encodes an adaptor protein that plays a signaling role in a number of cellular processes including cell adhesion, cell migration, and immune function (PMID: 11607838). CRKL amplification and/or overexpression has been observed in gastric cancer (PMID: 22591714, PMID: 31356198), lung cancer (PMID: 22586683), and laryngeal squamous cell carcinoma (PMID: 31913340).
Additional content available in CKB BOOST