Gene Detail

Contact

Missing content? – Request curation!

Request curation for specific Genes, variants, or PubMed publications.

Have questions, comments or suggestions? - Let us know!

Email us at : ckbsupport@jax.org

Gene Symbol CRKL
Synonyms
Gene Description CRKL, CRK like proto-oncogene, adaptor protein, encodes an adaptor protein that plays a signaling role in a number of cellular processes including cell adhesion, cell migration, and immune function (PMID: 11607838). CRKL amplification and/or overexpression has been observed in gastric cancer (PMID: 22591714, PMID: 31356198), lung cancer (PMID: 22586683), and laryngeal squamous cell carcinoma (PMID: 31913340).


Additional content available in CKB BOOST