Gene Detail
Contact
Missing content? – Request curation!
Request curation for specific Genes, Variants, or PubMed publications.
Have questions, comments, or suggestions? - Let us know!
Email us at : ckbsupport@jax.org
| Gene Symbol | CSNK1A1 | ||||||||||
| Synonyms | CK1 | CK1a | CKIa | HEL-S-77p | HLCDGP1 | PRO2975 | ||||||||||
| Gene Description | CSNK1A1, casein kinase 1 alpha 1, encodes a member of the CK1 protein family that functions as a signaling molecule involved in multiple cellular processes including proliferation, autophagy, cell survival, and immune response, and plays a role in the regulation of the Wnt and Hedgehog signaling pathways, Tp53, and Nf-kappaB (PMID: 29793495, PMID: 28969692). CSNK1A1 mutations have been identified in myelodysplastic syndrome (PMID: 25792355) and colorectal cancer (PMID: 27031502). | ||||||||||
|
|||||||||||
Additional content available in 
CKB BOOST
CKB BOOST
