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|Synonyms||CK1 | CK1a | CKIa | HEL-S-77p | HLCDGP1 | PRO2975|
|Gene Description||CSNK1A1, casein kinase 1 alpha 1, encodes a member of the CK1 protein family that functions as a signaling molecule involved in multiple cellular processes including proliferation, autophagy, cell survival, and immune response, and plays a role in the regulation of the Wnt and Hedgehog signaling pathways, Tp53, and Nf-kappaB (PMID: 29793495, PMID: 28969692). CSNK1A1 mutations have been identified in myelodysplastic syndrome (PMID: 25792355) and colorectal cancer (PMID: 27031502).|