Gene Detail
Contact
Missing content? – Request curation!
Request curation for specific Genes, Variants, or PubMed publications.
Have questions, comments, or suggestions? - Let us know!
Email us at : ckbsupport@jax.org
| Gene Symbol | CSNK2A1 | ||||||||||
| Synonyms | CK2A1 | Cka1 | Cka2 | CKII | OCNDS | ||||||||||
| Gene Description | CSNK2A1, casein kinase 2 alpha 1, is the alpha catalytic subunit of the constitutively active CK2 protein kinase that interacts with acidic substrates and plays a role in cell growth and proliferation, apoptosis, autophagy (PMID: 31277672, PMID: 31500224, PMID: 12244125, PMID: 32626654), and may regulate mTORC1 activity (PMID: 32626654). Overexpression of CSNK2A1 has been identified in various tumors, including lymphoma, breast, kidney, and lung cancer (PMID: 25541719). | ||||||||||
|
|||||||||||
Additional content available in 
CKB BOOST
CKB BOOST
