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Gene Symbol CCN2
Synonyms CTGF | HCS24 | IGFBP8 | NOV2
Gene Description CCN2, cellular communication network factor 2, encodes for a matricellular protein that is induced by growth factors and plays a role in cell adhesion, aggregation, and migration in a number of cell types (PMID: 25120383, PMID: 15371538, PMID: 18789696). CCN2 overexpression has been associated with a poor prognosis in a variety of tumor types, including chondosarcoma, pancreatic cancer, esophageal cancer, and breast cancer (PMID: 30158025).


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