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Gene Symbol BTLA
Synonyms BTLA1 | CD272
Gene Description BTLA, B and T lymphocyte associated, encodes an immune checkpoint receptor that plays a role in immune response suppression through inhibition of T-cell activation (PMID: 22205715, PMID: 31502146, PMID: 31753019). Overexpression of Btla has been identified in leukemia (PMID: 33917094), melanoma (PMID: 33718105), ovarian (PMID: 35204342), and colorectal cancers (PMID: 34217699).
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