Gene Detail

Gene Symbol DYRK1A
Synonyms DYRK | DYRK1 | HP86 | MNB | MNBH | MRD7
Gene Description DYRK1A, dual specificity tyrosine-(Y)-phosphorylation regulated kinase 1A, encodes for a protein kinase known to target genes involved in growth, development, cell proliferation, and apoptosis (PMID: 20167603). Overexpression of DYRK1A has been associated with cancer, but it also exhibits tumor suppressor characteristics, which is dependent on the cellular context (PMID: 25795597).
Entrez Id 1859
Chromosome 21
Map Location 21q22.13
Canonical Transcript NM_001396

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