Missing content? – Request curation!
Request curation for specific Genes, Variants, or PubMed publications.
Have questions, comments, or suggestions? - Let us know!
Email us at : firstname.lastname@example.org
|Synonyms||EPR-1 | ERT | ESE-1 | ESX|
|Gene Description||ELF3, E74 like ETS transcription factor 3, is a transcriptional activator involved in inflammation (PMID: 22157719), cell differentiation (PMID: 29523781), and cell cycle progression (PMID: 29050229). ELF3 overexpression has been implicated in ERBB2 (HER2) positive breast cancer progression (PMID: 29050229, PMID: 29187433) and hepatocellular carcinoma (PMID: 29523781), while decreased expression has been correlated with reduced survival in ovarian cancer (PMID: 28199976), and ELF3 amplification and hypomethylation in lung adenocarcinoma may be oncogenic (PMID: 31780666).|