Gene Detail

Gene Symbol ELF3
Synonyms EPR-1 | ERT | ESE-1 | ESX
Gene Description ELF3, ETS-related transcription factor Elf-3, is a transcriptional activator involved in inflammation (PMID: 22157719), cell differentiation (PMID: 29523781), and cell cycle progression (PMID: 29050229). ELF3 overexpression has been implicated in ERBB2 (HER2) positive breast cancer progression (PMID: 29050229, PMID: 29187433) and hepatocellular carcinoma (PMID: 29523781), while decreased expression has been correlated with reduced survival in ovarian cancer (PMID: 28199976).
Entrez Id 1999
Chromosome 1
Map Location 1q32.1
Canonical Transcript NM_004433

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