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|Synonyms||ERCC11 | FANCQ | RAD1 | XFEPS | XPF|
|Gene Description||ERCC4, ERCC excision repair 4, endonuclease catalytic subunit, is a component of the Ercc1-Xpf nuclease that nicks DNA at specific sites, thus is involved in DNA repair (PMID: 26074087). ERCC4 mutations results in xeroderma pigmentosum, Cockayne syndrome, Fanconi anemia, and XFE progeria and therefore, may be associated with increased cancer risk (PMID: 26074087).|