Missing content? – Request curation!
Request curation for specific Genes, Variants, or PubMed publications.
Have questions, comments, or suggestions? - Let us know!
Email us at : email@example.com
|Synonyms||ER | Era | ESR | ESRA | ESTRR | NR3A1|
|Gene Description||ESR1, estrogen receptor alpha, modulates response to estrogen and is used as a marker to predict response to endocrine therapy in breast cancer patients (PMID: 23542176, PMID: 26183887). ESR1 fusions are recurrent in breast cancer, and mutations in ESR1 have been associated with decreased response to endocrine therapy (PMID: 27372070, PMID: 26183887) in breast cancer (PMID: 31795152).|