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Gene Symbol FASN
Synonyms FAS | OA-519 | SDR27X1
Gene Description FASN, fatty acid synthase, converts acetyl-CoA and malonyl-CoA to palmitate in the synthesis of fatty acids (PMID: 30619288). Altered expression of Fasn in ovarian cancer may impair the anti-tumor response (PMID: 30619288) and development of Fasn inhibitors is an active area of investigation for Fasn-overexpressing tumors (PMID: 30578319, PMID: 30667213, PMID: 29779975, PMID: 29751678).
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