Gene Detail

Gene Symbol FOXO3
Synonyms AF6q21 | FKHRL1 | FKHRL1P2 | FOXO2 | FOXO3A
Gene Description FOXO3, forkhead box O3, encodes for a protein belonging to the Forkhead box O family of transcription factors, which plays a role in multiple cellular functions such as cell proliferation, apoptosis, autophagy, and metabolism (PMID: 24864265). Decreased expression of FOXO3 has been associated with worse prognosis in several tumor types including neuroblastoma, gastric, hepatocarcinoma, renal cell carcinoma, and breast cancer (PMID: 25678856).
Entrez Id 2309
Chromosome 6
Map Location 6q21
Canonical Transcript NM_001455

Additional content available in CKB BOOST