Missing content? – Request curation!
Request curation for specific Genes, Variants, or PubMed publications.
Have questions, comments, or suggestions? - Let us know!
Email us at : email@example.com
|Synonyms||AF6q21 | FKHRL1 | FKHRL1P2 | FOXO2 | FOXO3A|
|Gene Description||FOXO3, forkhead box O3, encodes for a protein belonging to the Forkhead box O family of transcription factors, which plays a role in multiple cellular functions such as cell proliferation, apoptosis, autophagy, and metabolism (PMID: 24864265). Overexpression of FOXO3 has been associated with worse prognosis in several tumor types including neuroblastoma, gastric, hepatocarcinoma (PMID: 32256814), renal cell carcinoma, and breast cancer (PMID: 25678856).|