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|Synonyms||AF6q21 | FKHRL1 | FKHRL1P2 | FOXO2 | FOXO3A|
|Gene Description||FOXO3, forkhead box O3, encodes for a protein belonging to the Forkhead box O family of transcription factors, which plays a role in multiple cellular functions such as cell proliferation, apoptosis, autophagy, and metabolism (PMID: 24864265). Decreased expression of FOXO3 has been associated with worse prognosis in several tumor types including neuroblastoma, gastric, hepatocarcinoma, renal cell carcinoma, and breast cancer (PMID: 25678856).|