Gene Detail

Contact

Missing content? – Request curation!

Request curation for specific Genes, variants, or PubMed publications.

Have questions, comments or suggestions? - Let us know!

Email us at : ckbsupport@jax.org

Gene Symbol CDK19
Synonyms bA346C16.3 | CDC2L6 | CDK11
Gene Description CDK19, cyclin-dependent kinase 19, is a component of the multiprotein Mediator complex (MED), which is an activator of RNA polymerase II (Pol II) and plays a role in regulation of gene transcription (PMID: 27678455). Overexpression of Cdk19 has been observed to correlate with increased aggressiveness and decreased survival of prostate cancer patients (PMID: 27678455, PMID: 29568371).


Additional content available in CKB BOOST