Missing content? – Request curation!
Request curation for specific Genes, variants, or PubMed publications.
Have questions, comments or suggestions? - Let us know!
Email us at : firstname.lastname@example.org
|Synonyms||CYTSA | GBBB2 | OBLFC1 | TBHS|
|Gene Description||SPECC1L, sperm antigen with calponin homology and coiled-coil domains 1 like, encodes a coiled-coil domain containing protein that plays a role in cytoskeletal reorganization (PMID: 21703590), regulating PI3K/Akt signaling, adherens junctions proteins (PMID: 26787558), and craniofacial development (PMID: 31943082, PMID: 30472488, PMID: 25357034). SPECC1L fusions have been identified in non-small cell lung cancer (PMID: 32216970), lung adenocarcinoma (PMID: 30683294), uterine cervical sarcoma (PMID: 31917708), and decreased expression has been observed in extra-cranial malignant rhabdoid tumors (PMID: 26977886).|