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Gene Symbol PIK3R5
Synonyms F730038I15Rik | FOAP-2 | p101 | P101-PI3K
Gene Description PIK3R5, phosphoinositide 3-kinase regulatory subunit 5, encodes the regulatory subunit of the PI3K gamma complex that is activated downstream of GPCRs to influence cell signaling, chemotaxis, and transformation (PMID: 24190998). PIK3R5 missense mutations have been identified in metastatic melanoma patients (PMID: 22912864).
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