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Gene Symbol PDCD4
Synonyms H731
Gene Description PDCD4, programmed cell death 4, regulates transcript translation through Cap-dependent initiation and may play a role in apoptosis and negative regulation of cell proliferation (PMID: 30518628, PMID: 29806708). Decreased expression of Pdcd4 has been observed in prostate cancer (PMID: 30518628), glioma (PMID: 29921407), may be diagnostic for colorectal cancer (PMID: 30243936), and is a putative tumor suppressor (PMID: 32195018).
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