Gene Detail


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Gene Symbol CTNNA3
Synonyms ARVD13 | VR22
Gene Description CTNNA3, catenin alpha 3, encodes a protein belonging to the catenin-alpha family that plays a role in cell adhesion (PMID: 21598020, PMID: 15366705), cardiomyocyte proliferation and cardiac function (PMID: 29467248, PMID: 25305307, PMID: 22421363). Mutations in CTNNA3 have been identified in laryngeal cancer (PMID: 24100690), decreased expression has been identified in hepatocellular carcinoma (PMID: 26882563), and a fusion with FGFR2 has been identified in neuroepithelial tumors (PMID: 27812792).

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