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|Synonyms||BRYLIB2 | H3-3A | H3.3B | H3F3B|
|Gene Description||H3-3B, H3 histone family member 3B, encodes the H3.3 histone variant, which is a component of the nucleosome, and plays a role in transcriptional regulation and genomic stability (PMID: 27894815, PMID: 25773741). H3-3B mutations have been associated with chondroblastoma, and have been identified in clear-cell chondrosarcoma and osteosarcoma (PMID: 24162739).|