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Gene Symbol HCK
Synonyms AIPCV | JTK9 | p59Hck | p61Hck
Gene Description HCK, HCK proto-oncogene, Src family tyrosine kinase, is a non-receptor tyrosine kinase that interacts with various proteins and regulates signaling transduction, and plays a role in cell adhesion and migration, lysosomal exocytosis, and phagocytosis (PMID: 18538446). Overexpression of HCK has been identified in acute myeloid leukemia and diffuse large B-cell lymphoma (PMID: 31790499).
Additional content available in CKB BOOST