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|Synonyms||bHLHe78 | HIF-1-alpha | HIF-1A | HIF-1alpha | HIF1 | HIF1-ALPHA | MOP1 | PASD8|
|Gene Description||HIF1A, hypoxia-inducible factor 1-alpha, induces transcription of many genes under hypoxic conditions and is a tumor antigen. Hif1a alters metabolism, promotes tumor progression, and targeting vaccines have been experimentally tested in TNBC (PMID: 23999440, EJC, Vol 72, Suppl. 1, p.S26, abstr. 210, 2017).|