Gene Detail
Contact
Missing content? – Request curation!
Request curation for specific Genes, Variants, or PubMed publications.
Have questions, comments, or suggestions? - Let us know!
Email us at : ckbsupport@jax.org
| Gene Symbol | PRMT2 | ||||||||||
| Synonyms | HRMT1L1 | ||||||||||
| Gene Description | PRMT2, protein arginine methyltransferase 2, is one of six Type I protein arginine methyltransferases (PMID: 30382083) that functions as a coactivator for nuclear receptors including estrogen receptor-alpha, progestrone receptor, and retinoic acid receptor-alpha (PMID: 24921003). Expression of alternative splice variants of PRMT2 have been associated with breast cancer (PMID: 24921003, PMID: 28677794) and overexpression has been associated with poor prognosis in glioblastoma (PMID: 30382083). | ||||||||||
|
|||||||||||
Additional content available in 
CKB BOOST
CKB BOOST
