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Gene Symbol HSPA5
Synonyms BIP | GRP78 | HEL-S-89n
Gene Description HSPA5, endoplasmic reticulum chaperone BiP, is an endoplasmic reticulum chaperone of the Hsp70 protein family (PMID: 28286085) that plays a role in regulation of the unfolded protein response (PMID: 27791469). Overexpression of Hspa5 has been observed in breast, prostate, lung, and liver cancer, where it may promote proliferation and metastasis (PMID: 28286085).
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