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Gene Symbol XIAP
Synonyms API3 | BIRC4 | hIAP-3 | hIAP3 | IAP-3 | ILP1 | MIHA | XLP2
Gene Description XIAP, X-linked inhibitor of apoptosis, is a member of the inhibitor of apoptosis protein (IAP) family that suppresses apoptosis through direct inhibition of caspases (PMID: 17016456), and also acts as a ubiquitin ligase regulating signaling pathways involved in immunity and inflammation (PMID: 25666262). XIAP expression has been identified in papillary thyroid cancer (PMID: 24124924) and chronic lymphocytic leukemia (PMID: 17283363).
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