Gene Detail
Contact
Missing content? – Request curation!
Request curation for specific Genes, Variants, or PubMed publications.
Have questions, comments, or suggestions? - Let us know!
Email us at : ckbsupport@jax.org
| Gene Symbol | HSP90AA1 | ||||||||||
| Synonyms | EL52 | HEL-S-65p | Hsp103 | HSP86 | Hsp89 | HSP89A | Hsp90 | HSP90A | HSP90N | HSPC1 | HSPCA | HSPCAL1 | HSPCAL4 | HSPN | LAP-2 | LAP2 | ||||||||||
| Gene Description | HSP90AA1, heat shock protein 90 alpha family class A member 1, encodes a cytosolic isoform of Hsp90, which functions as a molecular chaperone to regulate the activities of several cellular proteins (PMID: 26071189) and plays a role in regulating autophagy (PMID: 30153855). Overexpression of Hsp90aa1 has been associated with several tumor types (PMID: 26071189), including pancreatic and thymic carcinoma (PMID: 31814876), while decreased expression in squamous cell lung cancer has been associated with decreased survival (PMID: 32194709). | ||||||||||
|
|||||||||||
Additional content available in 
CKB BOOST
CKB BOOST
