Missing content? – Request curation!
Request curation for specific Genes, variants, or PubMed publications.
Have questions, comments or suggestions? - Let us know!
Email us at : firstname.lastname@example.org
|Synonyms||CD221 | IGFIR | IGFR | JTK13|
|Gene Description||IGF1R, insulin-like growth factor 1 receptor, is a receptor tyrosine kinase which activates MAPK, PI3K/AKT, and JAK/STAT pathways, promoting cell proliferation (PMID: 22520978). Overexpression of Igf1r has been observed in various tumors, including invasive bladder carcinoma (PMID: 30338346).|