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Gene Symbol IGF1R
Synonyms CD221 | IGFIR | IGFR | JTK13
Gene Description IGF1R, insulin-like growth factor 1 receptor, is a receptor tyrosine kinase which activates MAPK, PI3K/AKT, and JAK/STAT pathways, promoting cell proliferation (PMID: 22520978). Overexpression of Igf1r has been observed in various tumors, including invasive bladder carcinoma (PMID: 30338346).
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