Missing content? – Request curation!
Request curation for specific Genes, Variants, or PubMed publications.
Have questions, comments, or suggestions? - Let us know!
Email us at : firstname.lastname@example.org
|Synonyms||IBP2 | IGF-BP53|
|Gene Description||IGFBP2, insulin like growth factor binding protein 2, is a member of the IGF-binding protein (IGFBP) family that functions as a secretory and intracellular protein (PMID: 30626422) to regulate IGF and integrin pathways in modulation of cell growth and migration (PMID: 26317790). Overexpression of Igfbp2 has been observed in a number of tumor types including, ovarian, breast, colon, lung, glioma, prostate, and leukemia (PMID: 30626422, PMID: 26662106, PMID: 25774149).|