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Gene Symbol TNFRSF9
Synonyms 4-1BB | CD137 | CDw137 | ILA
Gene Description TNFRSF9, TNF receptor superfamily member 9, is a costimulatory molecule of the TNF receptor superfamily that activates cellular immunity against pathogens and tumor cells (PMID: 32505443, PMID: 30174217). Overexpression of TNFRSF9 has been identified in head and neck squamous cell carcinoma (PMID: 31593831), gliomas (PMID: 24606203), and follicular lymphoma (PMID: 23775959).
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