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Gene Symbol IRF2
Synonyms IRF-2
Gene Description IRF2, interferon regulatory factor 2, encodes a transcription factor that participates in both the activation and repression of genes, playing a role in the interferon response and cellular functions related to growth and apoptosis (PMID: 18514056, PMID: 18395009). Overexpression of Irf2 has been identified in a variety of tumor types including pancreatic cancer (PMID: 24632547), esophageal squamous cell carcinoma (PMID: 17363571), and colorectal cancer (PMID: 28465494).
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