Gene Detail

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Gene Symbol KRAS
Synonyms 'C-K-RAS | C-K-RAS | c-Ki-ras | c-Ki-ras2 | CFC2 | K-Ras | K-Ras 2 | K-RAS2A | K-RAS2B | K-RAS4A | K-RAS4B | KI-RAS | KRAS1 | KRAS2 | NS | NS3 | OES | RALD | RASK2
Gene Description KRAS, KRAS proto-oncogene, GTPase, is a member of the small GTPase superfamily and a key regulator of the MAPK, PI3K/AKT/mTOR pathways (PMID: 23622131) that plays a role in regulation of cell proliferation (PMID: 31988705). KRAS mutations are identified in a wide range of cancers (PMID: 28666118), including colorectal cancer (PMID: 31952666, PMID: 32241284), non-small cell lung cancer (PMID: 32062493, PMID: 32244355), and pancreatic cancer (PMID: 32005945).


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