Gene Detail


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Gene Symbol BCAM
Synonyms AU | B-CAM | CD239 | F8/G253 | LU | MSK19
Gene Description BCAM, basal cell adhesion molecule (Lutheran blood group), is a member of the immunoglobulin superfamily that functions as a receptor for laminin alpha5 and has a putative role in cell migration and metastasis (PMID: 24223164, PMID: 24036115). Overexpression of Bcam has been observed in metastatic gastric cancer (PMID: 31951095), bladder cancer (PMID: 28841878), and ovarian cancer (PMID: 24036115), and a BCAM-AKT2 has been reported in ovarian carcinoma (PMID: 25733895).
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