Gene Detail

Gene Symbol LYN
Synonyms JTK8 | p53Lyn | p56Lyn
Gene Description LYN, LYN proto-oncogene, Src family tyrosine kinase, is a non-receptor tyrosine kinase that plays a role in regulation of cell signaling and immune function (PMID: 25173936). Activating mutations in LYN are associated with drug resistance in breast cancer, and a LYN fusion with ETV6 has been observed in leukemia (PMID: 21492125, PMID: 25401474).
Entrez Id 4067
Chromosome 8
Map Location 8q12.1
Canonical Transcript NM_002350

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