Gene Detail
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| Gene Symbol | SMAD3 | ||||||||||
| Synonyms | HSPC193 | HsT17436 | JV15-2 | LDS1C | LDS3 | MADH3 | ||||||||||
| Gene Description | SMAD3, SMAD family member 3, is a transcription factor (PMID: 30589983) and mediator of TGF beta signaling (PMID: 23139211) that plays a role in inflammation (PMID: 30659096). A EWSR1-SMAD3 fusion has been identified in spindle cell tumors (PMID: 29309308) and somatic mutations have been identified in colorectal cancer (PMID: 23139211). | ||||||||||
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