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Gene Symbol SMAD3
Synonyms HSPC193 | HsT17436 | JV15-2 | LDS1C | LDS3 | MADH3
Gene Description SMAD3, SMAD family member 3, is a transcription factor (PMID: 30589983) and mediator of TGF beta signaling (PMID: 23139211) that plays a role in inflammation (PMID: 30659096). A EWSR1-SMAD3 fusion has been identified in spindle cell tumors (PMID: 29309308) and somatic mutations have been identified in colorectal cancer (PMID: 23139211).


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