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Gene Symbol MBNL1
Synonyms EXP | MBNL
Gene Description MBNL1, muscleblind-like splicing regulator 1, is an RNA binding protein that is involved in the metabolic regulation of precursor mRNA, mature mRNA, and RNA export, splicing, and stability (PMID: 30456384). A fusion of MBNL1-RAF1 has been reported in cancer cell lines (PMID: 25485619), MBNL1 confers cisplatin resistance in cervical cell cultures (PMID: 31791583), and alternatively spliced MBNL1 isoforms may be oncogenic or tumor suppressive (PMID: 30456384).
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