Gene Detail

Contact

Missing content? – Request curation!

Request curation for specific Genes, Variants, or PubMed publications.

Have questions, comments, or suggestions? - Let us know!

Email us at : ckbsupport@jax.org

Gene Symbol MLLT1
Synonyms ENL | LTG19 | YEATS1
Gene Description MLLT1, MLLT1 super elongation complex subunit, is also referred to as ENL and is a component of the super elongation complex and YEATS domain containing protein (PMID: 31857843) that activates transcription (PMID: 8080983) and regulates chromatin remodeling (PMID: 30066088). MLLT1 gene rearrangements with KMT2A are frequently observed in leukemia (PMID: 19262598, PMID: 30203571).
Additional content available in CKB BOOST