Gene Detail


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Gene Symbol MMP14
Synonyms MMP-14 | MMP-X1 | MT-MMP | MT-MMP 1 | MT1-MMP | MT1MMP | MTMMP1 | WNCHRS
Gene Description MMP14, matrix metallopeptidase 14, also referred to as MT1-MMP, is a member of the membrane-type matrix metalloproteinases family that is involved in degradation of extracellular matrices, therefore contributes to tumor cell metastasis (PMID: 25794647). Elevated Mmp14 expression has been identified in a variety of cancers, particularly in cancers of mesenchymal origin (PMID: 28390905).
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