Gene Detail

Gene Symbol MRE11
Synonyms ATLD | HNGS1 | MRE11A | MRE11B
Gene Description MRE11, MRE11 homolog, double strand break repair nuclease, functions as part of a complex involved in DNA double strand break repair, and plays a role in regulation of telomerase activity (PMID: 22914783). MRE11 aberrations are associated with breast and ovarian cancer (PMID: 25447316, PMID: 26436112).
Entrez Id 4361
Chromosome 11
Map Location 11q21
Canonical Transcript NM_005591

Additional content available in CKB BOOST