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Gene Symbol IFIT1B
Synonyms bA149I23.6 | IFIT1L
Gene Description IFIT1B, interferon-induced protein with tetratricopeptide repeats 1B, is a member of the IRF-inducible gene family that may play a role in the immune defense against RNA viruses (PMID: 27240734). Loss of Ifit1b, in conjunction with loss of Ifit1, Ifit2, and Ifit3, has been associated with resistance to Yervoy (ipilimumab) in a melanoma patient (PMID: 27667683).
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