Gene Detail

Gene Symbol ASPH
Synonyms AAH | BAH | CASQ2BP1 | FDLAB | HAAH | JCTN | junctin
Gene Description ASPH, aspartyl/asparaginyl beta-hydroxylase, hydroxylates certain residues within EGF-domain containing proteins, including Notch and Jagged to promote cell migration (PMID: 28985022). Altered ASPH expression has been observed in hepatocellular carcinoma (PMID: 24954865), cholangiocarcinoma (PMID: 26954680), and luminal B breast cancer (PMID: 28985022).
Entrez Id 444
Chromosome 8
Map Location 8q12.3
Canonical Transcript NM_004318

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