Gene Detail

Contact

Missing content? – Request curation!

Request curation for specific Genes, Variants, or PubMed publications.

Have questions, comments, or suggestions? - Let us know!

Email us at : ckbsupport@jax.org

Gene Symbol MST1R
Synonyms CD136 | CDw136 | NPCA3 | p185-Ron | PTK8 | RON | SEA
Gene Description MST1R, macrophage stimulating 1 receptor, encodes the receptor tyrosine kinase RON, which acts as a receptor for macrophage-stimulating protein and is involved in cell migration and differentiation (PMID: 21543897, PMID: 23792360). Alterations in MST1R have been associated with several tumor types (PMID: 23792360) and overexpression of Mst1r has been associated with pancreatic cancer progression (PMID: 30967626).
Additional content available in CKB BOOST