Gene Detail

Contact

Missing content? – Request curation!

Request curation for specific Genes, variants, or PubMed publications.

Have questions, comments or suggestions? - Let us know!

Email us at : ckbsupport@jax.org

Gene Symbol MYB
Synonyms c-myb | c-myb_CDS | Cmyb | efg
Gene Description MYB, MYB proto-oncogene, transcription factor, is a transcriptional activator that regulates cell differentiation and proliferation (PMID: 21196221) and is highly expressed in hematopoietic progenitor cells and plays a role in hematopoiesis (PMID: 28472346). MYB is dysregulated in several tumor types (PMID: 21196221), including leukemia and breast cancer (PMID: 30599775), and MYB fusions have been observed in hematological cancers (PMID: 30599775).


Additional content available in CKB BOOST