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Gene Symbol MYH11
Synonyms AAT4 | FAA4 | SMHC | SMMHC
Gene Description MYH11, myosin heavy chain 11, smooth muscle, encodes for the myosin heavy chain protein that plays a role in the contractility of smooth muscle (PMID: 21937134). MYH11 fusions with CBFB have been frequently found in acute myleoid leukemia (PMID: 14736823, PMID: 31353165) and frameshift mutations have been observed in gastric and colorectal cancers (PMID: 29517504).


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