Gene Detail


Missing content? – Request curation!

Request curation for specific Genes, variants, or PubMed publications.

Have questions, comments or suggestions? - Let us know!

Email us at :

Gene Symbol MYH11
Synonyms AAT4 | FAA4 | SMHC | SMMHC
Gene Description MYH11, myosin heavy chain 11, smooth muscle, encodes for the myosin heavy chain protein that plays a role in the contractility of smooth muscle (PMID: 21937134). MYH11 fusions with CBFB have been frequently found in acute myleoid leukemia (PMID: 14736823, PMID: 31353165) and frameshift mutations have been observed in gastric and colorectal cancers (PMID: 29517504).

Additional content available in CKB BOOST