Gene Detail

Gene Symbol NF2
Synonyms ACN | BANF | SCH
Gene Description NF2, neurofibromin 2, is a tumor suppressor that inhibits cell proliferation and promotes apoptosis through regulating cell-cell contact and gene expression (PMID: 22482125). Germline inactivating mutations of NF2 cause neurofibromatosis 2, while somatic mutations of NF2 are identified in a wide variety of tumors (PMID: 24393766).
Entrez Id 4771
Chromosome 22
Map Location 22q12.2
Canonical Transcript NM_000268


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