Missing content? – Request curation!
Request curation for specific Genes, variants, or PubMed publications.
Have questions, comments or suggestions? - Let us know!
Email us at : email@example.com
|Synonyms||CALJA | CD73 | E5NT | eN | eNT | NT | NT5 | NTE|
|Gene Description||NT5E (CD73), 5'-nucleotidase, converts adenosine monophosphate (AMP) to adenosine to regulate cellular homeostasis and functions as an immune checkpoint inhibitor (PMID: 29720980). NT5E (CD73) high expression in the tumor microenvironment has been implicated as a prognostic biomarker in a variety of tumor types, including colorectal, NSCLC, ovarian, TNBC, melanoma, renal, and gastric (PMID: 29914571, PMID: 28258700).|