Gene Detail


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Gene Symbol PAK3
Synonyms ARA | beta-PAK | bPAK | MRX30 | MRX47 | OPHN3 | PAK-3 | PAK3beta | XLID30
Gene Description PAK3, p21 p21 (RAC1) activated kinase 3, is a serine/threonine kinase that binds Rho GTPases to participate in signaling of cell migration and cytoskeletal reorganization (PMID: 23818969). PAK3 appears to play a role in cell transformation (PMID: 18639460, PMID: 23818969) and overexpression may promote tumorgenesis in pancreatic cancer cells (PMID: 31051214).
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