Missing content? – Request curation!
Request curation for specific Genes, Variants, or PubMed publications.
Have questions, comments, or suggestions? - Let us know!
Email us at : firstname.lastname@example.org
|Synonyms||ARA | beta-PAK | bPAK | MRX30 | MRX47 | OPHN3 | PAK-3 | PAK3beta | XLID30|
|Gene Description||PAK3, p21 p21 (RAC1) activated kinase 3, is a serine/threonine kinase that binds Rho GTPases to participate in signaling of cell migration and cytoskeletal reorganization (PMID: 23818969). PAK3 appears to play a role in cell transformation (PMID: 18639460, PMID: 23818969) and overexpression may promote tumorgenesis in pancreatic cancer cells (PMID: 31051214).|