Gene Detail

Contact

Missing content? – Request curation!

Request curation for specific Genes, variants, or PubMed publications.

Have questions, comments or suggestions? - Let us know!

Email us at : ckbsupport@jax.org

Gene Symbol PBX1
Synonyms CAKUHED
Gene Description PBX1, PBX homeobox 1, is a transcription factor that is involved in regulating the development of many processes such as hematopoiesis, skeleton patterning, and organogenesis of the pancreas and urogenital systems (PMID: 22125492). PBX1 fusions with E2A have been observed in pre-B-cell leukemia and PBX1 activity has been linked to multiple cancer types (PMID: 22125492, PMID: 1967983).


Additional content available in CKB BOOST