Missing content? – Request curation!
Request curation for specific Genes, Variants, or PubMed publications.
Have questions, comments, or suggestions? - Let us know!
Email us at : email@example.com
|Synonyms||CD288 | hTLR8 | IMD98|
|Gene Description||TLR8, toll like receptor 8, encodes a member of the endosomal toll-like receptor family of proteins that intracellularly plays a role in the detection of foreign single-strand RNA and subsequent activation of inflammatory cytokines (PMID: 18927625, PMID: 20652908, PMID: 23906644), and is involved in cross-talk with other endosomal toll-like receptor proteins (PMID: 23085951) and anti-tumor immunity (PMID: 25231413). TLR8 is overexpressed in pancreatic cancer (PMID: 26134824) and lung cancer (PMID: 22344343).|