Missing content? – Request curation!
Request curation for specific Genes, variants, or PubMed publications.
Have questions, comments or suggestions? - Let us know!
Email us at : email@example.com
|Synonyms||FBI-1 | FBI1 | LRF | pokemon | TIP21 | ZBTB7 | ZNF857A|
|Gene Description||ZBTB7A, zinc finger and BTB domain containing 7A, is a member of the POK family transcription repressors that regulates cell cycle, apoptosis, and hematopoietic cell lineage decision (PMID: 16204018, PMID: 23396304). ZBTB7A amplification and overexpression have been identified in breast (PMID: 20394500), ovarian (PMID: 21176152), prostate (PMID: 21251909), non-small cell lung cancer (PMID: 17907153), and diffuse large B cell lymphoma (PMID: 16204018), and decreased Zbtb7a expression has been identified in oral squamous cell carcinoma (PMID: 25439053).|