Gene Detail


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Gene Symbol ZBTB7A
Synonyms FBI-1 | FBI1 | LRF | MNDLFH | pokemon | TIP21 | ZBTB7 | ZNF857A
Gene Description ZBTB7A, zinc finger and BTB domain containing 7A, is a member of the POK family transcription repressors that regulates cell cycle, apoptosis, and hematopoietic cell lineage decision (PMID: 16204018, PMID: 23396304). ZBTB7A amplification and overexpression have been identified in breast (PMID: 20394500), ovarian (PMID: 21176152), prostate (PMID: 21251909), non-small cell lung cancer (PMID: 17907153), and diffuse large B cell lymphoma (PMID: 16204018), and decreased Zbtb7a expression has been identified in oral squamous cell carcinoma (PMID: 25439053).
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