Gene Detail
Contact
Missing content? – Request curation!
Request curation for specific Genes, Variants, or PubMed publications.
Have questions, comments, or suggestions? - Let us know!
Email us at : ckbsupport@jax.org
| Gene Symbol | FZR1 | ||||||||||
| Synonyms | CDC20C | CDH1 | DEE109 | FZR | FZR2 | HCDH | HCDH1 | ||||||||||
| Gene Description | FZR1, fizzy and cell division cycle 20 related 1, is a coactivator of the anaphase-promoting complex/cyclosome (APC/C) that is involved in regulating the onset of DNA replication (PMID: 19861496). Overexpression of Fzr1 has been identified in multiple myeloma (PMID: 27655696) and B-cell acute leukemia (PMID: 28143883), and FZR1 mutations have been identified in male breast cancer (PMID: 31203460). | ||||||||||
|
|||||||||||
Additional content available in 
CKB BOOST
CKB BOOST
