Gene Detail
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| Gene Symbol | UBR5 | ||||||||||
| Synonyms | DD5 | EDD | EDD1 | HYD | ||||||||||
| Gene Description | UBR5, ubiquitin protein ligase E3 component n-recognin 5, is a key regulator of the ubiquitin-proteasome system, thus plays a role in diverse biological processes including development and turmorigenesis (PMID: 26464214). Amplification of UBR5 has been reported in breast and ovarian cancer, and UBR5 mutations are frequently identified in mantle cell lymphoma (PMID: 26464214). | ||||||||||
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