Gene Detail

Gene Symbol ABCB1
Synonyms ABC20 | CD243 | CLCS | GP170 | MDR1 | P-GP | PGY1
Gene Description ABCB1, ATP binding cassette subfamily B member 1, is a membrane-bound ABC drug transport protein involved in movement of various compounds out of the cell (PMID: 27449595, PMID: 27180306). Abcb1 activity is associated with multidrug resistance in cancer (PMID: 27449595, PMID: 27180306, PMID: 30176891) and may predict toxicity (PMID: 30213564).
Entrez Id 5243
Chromosome 7
Map Location 7q21.12
Canonical Transcript NM_000927

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